1Preparation
When traveling to a new land, it’s good to make some preparations.
- Safety
- Medical screening
- Set, setting, and intention
Use Entheo's guidebooks to take you through a life-changing psychedelic experience.
Go at your own pace
Our interactive guide takes you through preparation, journey day, sitter support and integration. Make your own plan, reflect as you go, and download checklists to keep close.
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1When traveling to a new land, it’s good to make some preparations.
2It’s time to take off. Set the right trajectory.
3Okay. Ya. Wow. Let's make sense and integrate.

Psilocybin containing mushrooms and their psychoactive properties have been used for millennia for healing and transformation. Psilocybin, when ingested, is converted to psilocin and interacts primarily with serotonin receptors. The effect is a non-ordinary state of consciousness that lasts for about 6 hours. In research, Psilocybin’s therapeutic potential is most noted for treatment-resistant depression and illness-related anxiety.
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LSD is synthesized from an extraction of ergot–a fungus that grows on grain. Like psilocybin, LSD affects serotonin receptors and occasions psychedelic experiences that last for about 10-12 hours. In research, LSD’s therapeutic potential is most noted for alcohol use disorder and anxiety.
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MDMA is different. It’s referred to as an empathogen vs a psychedelic, and this fits. It can alter empathy, mood and social experience, with effects that vary by person and circumstance. MDMA, when used for self-discovery, may help one gain insights, find clarity and embrace difficult memories with empathy and acceptance. In research, MDMA is most noted for good outcomes in people with post-traumatic stress disorder when combined with psychotherapy.
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